How Bri Brennan is Using AI to Redesign Mental Health Care

Chief Innovation Officer at OnTrak Health

Author

Danny Nathan
June 26, 2025 • Estimated Reading Time: 5 minutes

Why you should watch it ☝️

What if your healthcare provider knew you were struggling before you did?

That’s not sci-fi. It’s what Bri Brennan is building at OnTrak Health using AI, real-time data, and a mental health digital twin that updates dynamically with every touchpoint, prescription refill, and environmental risk factor.

This episode is a clinic on how to execute innovation inside a typically risk-averse, heavily regulated industry. Bri doesn’t pitch theory. She shares what’s working, what’s failed, and what’s coming next, including:

  • Why most healthcare AI fails (and how they built one that doesn’t)

  • How they predict undiagnosed behavioral conditions before a single symptom is reported

  • The one test every tech pilot has to pass to scale inside OnTrak

  • What it really takes to earn trust from skeptical patients getting cold-called with a care offer

If you’re tired of vague talk about innovation and want to see what it actually takes to pull it off in the real world, start here.

I want to talk to you, Innovators!

Here’s what we covered in Sunday’s newsletter edition…

Lean Startup is Bullshit

I recently had an interesting exchange with a respected advisor in the startup space. The statement that jumped out at me? “Lean Startup is Bullshit.”

My immediate reaction was, “Whoa, whoa, whoa. You’re dumping on one of the most widely respected and highly touted startup frameworks ever written.” But if you step back and think about it, Lean really has become bullshit.

This week, we dig into why.

Here’s what you’ll find:

  • This Week’s Article: Lean Startup is Bullshit

  • Share This: How do we define “product?”

  • Case Study: How W.L. Gore Builds Startups from the Inside

Catch previous episodes of the Podcast here:

How Alex Fleischer Helps Corporates Find the Right Startup Match

Discover how Alex Fleischer helps Fortune 500 companies navigate startup innovation, break free from pilot purgatory, and transform curiosity into operational change.

www.innovatedisruptordie.com/p/how-alex-fleischer-helps-corporates-find-the-right-startup-match-74ebb14758c9b6fa

Why JT White Hates the Word "Disrupt"

Discover why JT White challenges the overused "disrupt" narrative and explores true innovation's meaning through AI-driven technology and product accessibility.

www.innovatedisruptordie.com/p/why-jt-white-hates-the-word-disrupt

The Podcast is Here 🎙️

Dive into the debut of "Innovate, Disrupt, or Die" podcast as host Danny Nathan shares his unique journey, insights, and vision in this candid, self-interviewed first episode.

www.innovatedisruptordie.com/p/the-podcast-is-here

Have you seen our Resource Library?

Here’s what you’ll find:

  • The Innovate, Disrupt, or Die GPT

  • The New Venture Assessment GPT

  • Whitepaper: Beyond Buzzwords: Driving Tangible and Repeatable Innovation in Business

  • Whitepaper: Beyond the "Big 4": How Technology Drives Sports from Niche to Notable

  • Whitepaper: An Executive's Guide to Internal Process Innovation

  • Business Model Template for SaaS and Services Businesses

  • Innovation Premium Estimator Model

Refer 3 friends to Innovate, Disrupt, or Die and you can earn a month of free access to either of our unique, highly trained custom GPTs.

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